@article{17647,
  keywords = {Humans, leprosy, Mycobacterium leprae, Nasal Mucosa, Skin, Sulfones},
  author = {QUAGLIATO R and Bechelli L M and Almeida J O and Araujo Arantes M A},
  title = {Bacteriological status (point prevalence) of lepromatous outpatients under sulfone treatment.},
  abstract = {<p>The study concerns 337 outpatients with lepromatous leprosy who had been receiving dapsone treatment for 1-26 years-69% of them regularly and 31% irregularly. Routine bacterial examination (10 min per slide) by a paramedical technician showed only 50% of these patients to be bacteriologically positive. This rate attained 99% when each slide was examined for 30-60 min by a qualified bacteriologist. Other factors-apart from the limited action of sulfones-might account for these unexpected results: the material was collected by an experienced leprologist; the disease was still clinically active in 75% of the patients; about 25% of them had been treated for only 1-4 years; and the intake of dapsone in long-term treatment gradually decreases.</p>},
  year = {1975},
  journal = {Bulletin of the World Health Organization},
  volume = {52},
  pages = {57-62},
  month = {1975},
  issn = {0042-9686},
  url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366341/pdf/bullwho00463-0067.pdf},
  language = {eng},
}