@article{17546, keywords = {Adult, Aged, Epitopes, HLA Antigens, Humans, Japan, leprosy, Lymphocytes, Middle Aged, Phenotype, Tuberculosis}, author = {Takata H and Sada M and Ozawa S and Sekiguchi S}, title = {HLA and mycobacterial infection: increased frequency of B8 in Japanese leprosy.}, abstract = {

A total of 60 leprosy patients, 28 of lepromatous and 32 of tuberculoid form, and 70 active tuberculosis patients was compared with a control of 184 for 34 HLA specificities. The most interesting finding was an increased frequency (10.0%) for HLA-B8 (corrected P = 0.062, relative risk = 20.3) in the leprosy patients as compared with the control group, despite the fact that the frequency of HLA-B8 was extremely low in Japanese. Furthermore, all leprosy patients with B8 had leprous member(s) in their family.

}, year = {1978}, journal = {Tissue antigens}, volume = {11}, pages = {61-4}, month = {1978 Jan}, issn = {0001-2815}, doi = {10.1111/j.1399-0039.1978.tb01225.x}, language = {eng}, }