@article{17024, keywords = {BCG Vaccine, Child, Preschool, Humans, leprosy, Lymphocyte Activation, Male}, author = {Stoner G L and Belehu A and Nsibambi J and Warndorff J}, title = {Borderline tuberculoid leprosy following BCG vaccination. A case report.}, abstract = {

Borderline tuberculoid leprosy was diagnosed clinically and histologically in a four year-old boy about 6 months after intradermal vaccination with BCG. His mother reported that a lesion began to appear above the vaccination site on the arm 2 weeks after the vaccination, and a second lesion appeared on the chin 2 months later. Responses in the lymphocyte transformation test to sonicated Mycobacterium leprae, BCG, and to PPD were consistent with a tuberculoid leprosy infection. Precipitation of BT leprosy by intradermal BCG infection may possibly represent the overcoming of a phase of primary suppression in an individual who might otherwise have progressed toward lepromatous leprosy. The implications of this hypothesis for the planning of a controlled trial of an anti-leprosy vaccine are discussed.

}, year = {1981}, journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association}, volume = {49}, pages = {16-20}, month = {1981 Mar}, issn = {0148-916X}, url = {http://ila.ilsl.br/pdfs/v49n1a03.pdf}, language = {eng}, }