@article{1699,
  keywords = {Adolescent, Adult, Aged, Agglutination Tests, Analysis of Variance, Antibodies, Bacterial, Antigens, Bacterial, Child, Child, Preschool, Drug Monitoring, Female, Glycolipids, Humans, Leprostatic Agents, leprosy, Male, Middle Aged, Mycobacterium leprae, Sensitivity and Specificity},
  author = {Kampirapap K},
  title = {Mycobacterium leprae particle agglutination in diagnosis and monitoring of treatment of leprosy.},
  abstract = {<p>IgM antibody levels against PGL-1 antigen were measured by M. leprae particle agglutination (MLPA) in 156 untreated leprosy patients. The seropositivity rate was much higher in newly untreated MB patients (84.7%) than in PB patients (19.7%). The mean MLPA titers in MB and PB declined significantly after 1 month of MDT (p < 0.001). Seropositivities in control serum specimens were 11.3 per cent in active pulmonary tuberculosis patients, 2.6 per cent in dermatologic patients and 4.4 per cent in a healthy population, in low titers. The study confirms that, anti PGL-1 assay using MLPA is a sensitive and specific diagnostic tool for the diagnosis of leprosy especially MB patients. Additionally, it provides an alternative tool in monitoring leprosy patients under MDT.</p>},
  year = {1999},
  journal = {Journal of the Medical Association of Thailand = Chotmaihet thangphaet},
  volume = {82},
  pages = {1020-4},
  month = {1999 Oct},
  issn = {0125-2208},
  language = {eng},
}