@article{16853,
  keywords = {Adult, Chemotaxis, Leukocyte, Griseofulvin, Humans, leprosy, Male},
  author = {Shulman D G and Wilkinson R D and Nguyen N},
  title = {Leprosy downgrading reaction associated with griseofulvin.},
  abstract = {<p>A dramatic alteration from clinically subpolar tuberculoid leprosy toward subpolar lepromatous leprosy was observed during griseofulvin therapy in a 29-year-old man, despite apparently normal cell-mediated immunity. To our knowledge, this is the first reported case of a downgrading reaction associated with griseofulvin. It is possible that this reaction was due to inhibition of polymorphonuclear leukocyte chemotaxis by griseofulvin.</p>},
  year = {1982},
  journal = {Archives of dermatology},
  volume = {118},
  pages = {909-12},
  month = {1982 Nov},
  issn = {0003-987X},
  language = {eng},
}