@article{16831,
  keywords = {Animals, Dapsone, Drug Interactions, Drug Therapy, Combination, Isoniazid, Isonicotinic Acids, leprosy, Mice, Mycobacterium, Mycobacterium leprae, Prothionamide},
  author = {Pattyn S R and Portaels F and Van Loo G and Van den Breen L},
  title = {Activity of the combination of isoniazid, protionamide and dapsone against Mycobacterium leprae and some other mycobacteria.},
  abstract = {<p>No additive effect was found at the addition of isoniazid to either dapsone or protionamide against M. leprae and against highly dapsone-sensitive in vitro growing Mycobacterium sp. strains. It is concluded that the indication of the administration of isoniazid in leprosy is extremely limited and could only be envisaged as a companion drug in combined therapy of dapsone-resistant multibacillary leprosy in light-skinned people, when aminoglycosides cannot be administered.</p>},
  year = {1981},
  journal = {Arzneimittel-Forschung},
  volume = {31},
  pages = {2155-7},
  month = {1981},
  issn = {0004-4172},
  language = {eng},
}