@article{16628,
  keywords = {Antibodies, Bacterial, Biopsy, Culture Techniques, Humans, Immunoglobulin G, leprosy, Mycobacterium leprae, Skin},
  author = {Lai A Fat R F and Chan Pin Jin J and Furth R and Harboe M},
  title = {In vitro synthesis of anti-mycobacterial antibodies in biopsies from skin lesions of leprosy patients.},
  abstract = {<p>To demonstrate local synthesis of anti-Mycobacterium leprae antibodies, biopsies from skin lesions of leprosy patients were cultured in vitro in a medium containing 14C-labeled lysine and isoleucine, and the culture fluids were analyzed by crossed immunoelectrophoresis with intermediate gel and autoradiography. The results show that anti-M. leprae antibodies were synthesized in vitro in the biopsies from the skin lesions of leprosy patients and that the specificity of the locally produced antibodies varied from patient to patient.</p>},
  year = {1980},
  journal = {Infection and immunity},
  volume = {27},
  pages = {297-301},
  month = {1980 Feb},
  issn = {0019-9567},
  url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC550764/pdf/iai00170-0015.pdf},
  language = {eng},
}