@article{16576, keywords = {HLA Antigens, Histocompatibility Antigens Class II, Histocompatibility Testing, Humans, Japan, leprosy, Phenotype}, author = {Izumi S and Sugiyama K and Matsumoto Y and Ohkawa S}, title = {Analysis of the immunogenetic background of Japanese leprosy patients by the HLA system.}, abstract = {

295 lepromatous and 74 tuberculoid leprosy patients were typed for HLA-A, -B and -C and compared to 110 healthy controls. It was found that frequency of HLA-B7 was significantly high and that of Bw54 was significantly low in lepromatous leprosy. HLA-DR and MT types were investigated in 84 lepromatous and 28 tuberculoid patients and compared to 55 controls. Both lepromatous and tuberculoid patients showed a marked increase in DR2 frequency. The relative risk is 8.7 and 5.9. Lepromatous leprosy showed an increase in frequency of MT1 and decreases in those of DRw9 and MT3 too.

}, year = {1982}, journal = {Vox sanguinis}, volume = {42}, pages = {243-7}, month = {1982}, issn = {0042-9007}, doi = {10.1111/j.1423-0410.1982.tb00751.x}, language = {eng}, }