@article{16552,
  keywords = {Adolescent, Adult, Aged, Female, Humans, Immunity, Cellular, leprosy, Male, Middle Aged, Rosette Formation, T-Lymphocytes},
  author = {Lim S D and Woo C S and Youn J I and Kim Y W and Kim D I and FUSARO R M},
  title = {Leprosy. XII. T-cell subsets in lepromatous leprosy.},
  abstract = {<p>The authors quantitated T-rosette-forming cell (TRFC) and T-cell subsets (T mu, T gamma) in the peripheral blood of twenty patients with lepromatous leprosy. The results obtained in their studies are as follows: (1) They reconfirmed the low levels of TRFC in patients with lepromatous type of leprosy; (2) T-cell subsets, both T mu (helper) and T gamma (suppressor) cells, showed lower levels in all patients with lepromatous leprosy than mean values of normal healthy controls; (3) The degree of decreased levels of T mu cells (96%) was more severe than other parameters TRFC (70%) and T gamma cells (47%) in all patients with lepromatous leprosy; and (4) It may be concluded that the alteration of the T-cell subset, T mu-cells, reflects a more fundamental abnormality than TRFC aberration in demonstrating the impairment of cell-mediated immunity in patients with lepromatous leprosy.</p>},
  year = {1982},
  journal = {International journal of dermatology},
  volume = {21},
  pages = {458-64},
  month = {1982 Oct},
  issn = {0011-9059},
  doi = {10.1111/j.1365-4362.1982.tb03182.x},
  language = {eng},
}