@article{16541, keywords = {Adult, Dapsone, Erythema Nodosum, Female, Humans, Ischemia, leprosy, Lymphopenia, Male, Middle Aged, Necrosis, Retrospective Studies, Skin, Thalidomide}, author = {Rea T H and Levan N E}, title = {Lucio's phenomenon and diffuse nonnodular lepromatous leprosy.}, abstract = {
The records of ten patients with Lucio's phenomenon showed clinical and histopathological changes similar to those described by others. Lucio's phenomenon is a syndrome distinct from erythema nodosum leprosum as indicated by an absence of fever, leukocytosis and tenderness, a failure to respond to thalidomide, and a restriction to patients with diffuse nonnodular lepromatous leprosy. Lymphopenia associated with splenomegaly in three patients and glomerulonephritis in one patient were unexpected findings of unknown relevance.
}, year = {1978}, journal = {Archives of dermatology}, volume = {114}, pages = {1023-8}, month = {1978 Jul}, issn = {0003-987X}, language = {eng}, }