@article{16369,
  keywords = {Animals, Bacteria, Dapsone, Escherichia coli, Lasers, leprosy, Mass Spectrometry, Mice, Mycobacterium leprae, Mycobacterium tuberculosis},
  author = {Seydel U and Lindner B and Seydel J K and Brandenburt K},
  title = {Detection of externally induced impairments in single bacterial cells by laser microbe mass analysis.},
  abstract = {<p>Applying the laser microbe mass analyzer method (LAMMA), mass spectra (fingerprints) were taken from single bacterial cells not treated or treated with high temperature, X-irradiation, isonicotinic acid hydrazide (INH), or diaminodiphenylsulfone (DDS). Spectra of treated cells ("M. lufu," M. tuberculosis H37Ra, E. coli) differ from those of controls in that the K+/Na+ ratio was smaller and in that the intensities of peaks with m/e greater than 100 were lower. From the results with M. leprae the possible application of this new method for monitoring the effectiveness of leprosy therapy is proposed.</p>
},
  year = {1982},
  journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association},
  volume = {50},
  pages = {90-5},
  month = {1982 Mar},
  issn = {0148-916X},
  url = {http://ila.ilsl.br/pdfs/v50n1a13.pdf},
  language = {eng},
}