@article{16283, keywords = {Cell Migration Inhibition, Haptens, Humans, Lactones, leprosy, Leukocytes, Mycobacterium leprae, Tetanus Toxoid}, author = {Fotedar A and Mustafa A S and Narang B S and Talwar G P}, title = {Improved leucocyte migration inhibition response of leucocytes from lepromatous leprosy patients with hapten modified M. leprae.}, abstract = {

Two acetoacetylated derivatives of Mycobacterium leprae with variable hapten groups and a conjugate with tetanus toxoid were prepared. These were tested as antigens along with unmodified M. leprae in the leucocyte migration inhibition response of leucocytes from clinically, bacteriologically and histopathologically confirmed cases of lepromatous leprosy. LMI response was poor with M. leprae, but was significantly enhanced with acetoacetylated M. leprae.

}, year = {1982}, journal = {Clinical and experimental immunology}, volume = {49}, pages = {317-24}, month = {1982 Aug}, issn = {0009-9104}, url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1536491/pdf/clinexpimmunol00167-0063.pdf}, language = {eng}, }