@article{16128, keywords = {Adult, Dapsone, Dinitrochlorobenzene, Humans, Irritants, Lepromin, leprosy, Male, Neuritis, Nitrobenzenes, Skin Tests, Tuberculin Test}, author = {Malhotra B and Das K D and Tutakne M A and Aggarwal S K}, title = {Precipitation of type-I (upgrading) reaction in leprosy by skin testing with antigen and irritants.}, abstract = {
Twenty patients of various types of leprosy were skin tested with lepromin, PPD and DNCB to assess their immunological status. Two of the twenty (18 BT; 2 BB) patients belonging to BT type developed signs of acute neuritis of sudden onset about 4 weeks after the test with DNCB, lepromin and PPD. The patients were on DDS therapy already for the last 3-4 months. Presumably DNCB, PPD or lepromin testing had precipitated the reaction. A suggestion is made that lepromin a lower concentration could be used initially and if it gives negative reaction, a higher concentration may be used as in case of PPD testing, particularly in TT and BT cases already put on treatment.
}, year = {1983}, journal = {Leprosy in India}, volume = {55}, pages = {305-9}, month = {1983 Apr}, issn = {0024-1024}, language = {eng}, }