@article{16075, keywords = {Alanine Transaminase, Alkaline Phosphatase, Aspartate Aminotransferases, Bilirubin, Blood Proteins, Clofazimine, Dapsone, Humans, leprosy, Liver, Liver Function Tests}, author = {Bulakh P M and Kowale C N and Ranade S M and Burte N P and Chandorkar A G}, title = {The effect of clofazimine on liver function tests in lepra reaction (ENL).}, abstract = {

Twenty patients with suspected DDS resistance and repeated attacks of lepra reactions were selected for the study. Clofazimine was administered in different doses over a period of 12 months. Elevated levels of transaminases and Alkaline phosphatase prior therapy attained values to near normalcy. Progressive fall in serum Bilirubin and Proteins with normal A/G ratio at the end of therapy was also observed. Clofazimine by its anti-inflammatory and antibacterial action could inhibit the process of liver damage and happened to have minimal deleterious effect on liver by studying the liver function tests.

}, year = {1983}, journal = {Leprosy in India}, volume = {55}, pages = {714-8}, month = {1983 Oct}, issn = {0024-1024}, language = {eng}, }