@article{16032, keywords = {Adolescent, Adult, Alpha 1-Antitrypsin, Child, Erythema Nodosum, Female, Humans, leprosy, Male, Middle Aged}, author = {Yemul V L and Sengupta S R and Dhole T N}, title = {Protease inhibitors activity in lepromatous leprosy and lepra reaction.}, abstract = {
Serum alpha one antitrypsin levels were measured in 50 healthy age and sex matched controls with 45 lepromatous leprosy cases and 5 cases of lepra reaction. It was noted that the mean level in healthy controls was 281.00 mg%, while the mean levels in LL patients was 421.00 mg% and in LR 570.00 mg%. The elevation of Alpha one antitrypsin was statistically significant in LL patients. It is possible that the rise is a reaction to release of proteases and or higher complement activity, which are the results of a high bacillary loading to formation of immune complexes.
}, year = {1983}, journal = {Leprosy in India}, volume = {55}, pages = {91-4}, month = {1983 Jan}, issn = {0024-1024}, language = {eng}, }