@article{1593, keywords = {Adult, Biomarkers, Female, Humans, leprosy, Male, Middle Aged, Nitric Oxide, Prognosis, Recurrence, Sensitivity and Specificity, Severity of Illness Index, Statistics, Nonparametric}, author = {Schön T and Gebre N and Sundqvist T and Habetmariam H S and Engeda T and Britton S}, title = {Increased levels of nitric oxide metabolites in urine from leprosy patients in reversal reaction.}, abstract = {
We measured the metabolites of NO [nitrite (NO2-) and nitrate (NO3-)] in urine from Ethiopian patients suffering from leprosy. The urinary level of NO2-/NO3- in a group of healthy Ethiopians was 1020 +/- 471 microM (n = 22). Leprosy patients in reversal reaction had significantly higher levels of NO2-/NO3- (1817 +/- 492 microM, p < 0.001, n = 12) than both the control group and leprosy patients who were not in reversal reaction (1079 +/- 446 microM, n = 12). We conclude that the reversal reaction in leprosy in associated with increased urinary levels of nitric oxide metabolites.
}, year = {1999}, journal = {Leprosy review}, volume = {70}, pages = {52-5}, month = {1999 Mar}, issn = {0305-7518}, url = {http://leprev.ilsl.br/pdfs/1999/v70n1/pdf/v70n1a11.pdf}, doi = {10.5935/0305-7518.19990011}, language = {eng}, }