@article{15815,
  keywords = {Antigen-Antibody Complex, Biopsy, Erythema Nodosum, Glomerulonephritis, Humans, Immune Complex Diseases, Kidney, leprosy, Male, Middle Aged},
  author = {Ng W L and Scollard D M and Hua A},
  title = {Glomerulonephritis in leprosy.},
  abstract = {<p>A renal biopsy from a patient with lepromatous leprosy but no history of erythrema nodosum leprosum (ENL) showed histologic, immunofluorescent, and ultrastructural features typical of immune-complex glomerulonephritis. A literature review found reports of 187 renal biopsies from leprosy patients, with glomerulonephritis in 31% of the cases, and a variety of other renal lesions. This accumulated evidence demonstrates that, contrary to widely held opinion, there is no association between glomerulonephritis and a history of ENL. Furthermore, it suggests that glomerulonephritis in leprosy patients has a similar incidence in lepromatous and non-lepromatous cases. These observations have an important bearing on concepts regarding the pathogenesis of immune complex glomerulonephritis in leprosy and the humoral immune mechanisms in patients with leprosy.</p>},
  year = {1981},
  journal = {American journal of clinical pathology},
  volume = {76},
  pages = {321-9},
  month = {1981 Sep},
  issn = {0002-9173},
  doi = {10.1093/ajcp/76.3.321},
  language = {eng},
}