@article{15764, keywords = {Antibodies, Monoclonal, Antigens, Bacterial, Corynebacterium, Enzyme-Linked Immunosorbent Assay, Humans, leprosy, Mycobacterium bovis, Mycobacterium leprae}, author = {Papa F P and Rauzier J Y and David H L}, title = {Occurrence of antigen BCG 60 in leprosy derived corynebacteria and other coryneforms.}, abstract = {

Previous studies have shown that anti BCG 60 monoclonal antibody could recognize major antigen A 7 of M. leprae. In the present investigation we attempted to search the presence of the same antigen from the strains of Leprosy Derived Corynebacteria (LDC+), which were isolated from leprosy lesions and were supposed to be the cultivable form of the leprosy bacillus. A comparative study was equally performed on 7 strains of Corynebacteria which were isolated in France and had no relation with leprosy patients (LDC-). Utilizing the ELISA technique with an anti BCG 60 monoclonal antibody, it was found that all the three LDC+ strains contained an antigenic determinant common to M. leprae, however no LDC+ specificity was found as this antigenic determinant was also revealed on two LDC- strains.

}, year = {1984}, journal = {Acta leprologica}, volume = {2}, pages = {351-8}, month = {1984 Oct-Dec}, issn = {0001-5938}, language = {eng}, }