@article{15733,
  keywords = {Humans, In Vitro Techniques, leprosy, Macrophages, Mycobacterium leprae, Phenotype},
  author = {Freire-Maia D V},
  title = {[Familial analysis of the in vitro behavior of human macrophages against Mycobacterium leprae].},
  abstract = {<p>The lysogenic capacity of human macrophages facing M. leprae in vitro may be dependent on an important genetic component. Although the family aggregation of the trait is demonstrated, this is a necessary but not sufficient condition to prove genetic influence. The data do not fit some simple genetic models (autosomal dominant or incompletely dominant gene; dominant or recessive sex-linked gene). The results obtained are consistent with the hypothesis that the macrophages' lysogenic capacity is mainly due to a major gene with variable expressivity. This hypothesis may be too simple to account for the whole variability detected and therefore must be considered just as a working hypothesis.</p>},
  year = {1983},
  journal = {Hansenologia internationalis},
  volume = {8},
  pages = {91-100},
  month = {1983 Dec},
  issn = {0100-3283},
  language = {por},
}