@article{15698,
  keywords = {Cell Membrane, Humans, Immune Tolerance, Immunity, Cellular, In Vitro Techniques, leprosy, Macrophages, Mycobacterium leprae, Receptors, Concanavalin A, Receptors, Fc},
  author = {Salgame P R and Birdi T J and Lad S J and Mahadevan P R and Antia N H},
  title = {Mechanism of immunosuppression in leprosy--macrophage membrane alterations.},
  abstract = {<p>L-Lysate induced macrophage membrane alteration was studied using 3 membrane markers: (i) Fc receptor, (ii) Concanavalin A (Con A) receptor, and (iii) M. leprae adherence to macrophage membrane. The data indicate that L-lysate induces membrane perturbation of normal macrophages. The alteration can be reversed with trypsin and colchicine. Membrane alteration observed may lead to defective macrophage participation in a cell-mediated immune reaction.</p>},
  year = {1984},
  journal = {Journal of clinical & laboratory immunology},
  volume = {14},
  pages = {145-9},
  month = {1984 Jul},
  issn = {0141-2760},
  language = {eng},
}