@article{15676,
  keywords = {Animals, leprosy, Mice, Mice, Inbred Strains, Mycobacterium leprae},
  author = {Vaishnavi C and Kaur S and Kumar B and Ganguly N K and Chakravarti R N},
  title = {Trophic changes and extensive dissemination in normal mice infected with human Mycobacterium leprae.},
  abstract = {<p>Closely bred Swiss albino normal mice (Lecca Strain) were inoculated in the footpad with M. leprae, at room temperature. The animals were harvested at 3, 6 and 9 months post inoculation, and bacillary counts were made. Trophic changes were observed in the tail-tips, ears, footpads and forepaws 12-14 months post inoculation in a group which was allowed to survive. The histopathological changes and bacillary infiltration was found in many tissues/organs. The possibility of studying this normal strain of mice as an experimental model for human leprosy has been discussed.</p>},
  year = {1984},
  journal = {Indian journal of leprosy},
  volume = {56},
  pages = {742-7},
  month = {1984 Oct-Dec},
  issn = {0254-9395},
  language = {eng},
}