@article{15479, keywords = {Animals, Collagen, Fibrin, Fluorescent Antibody Technique, Granuloma, Immunity, Cellular, Mice, Mice, Inbred Strains, Mycobacterium Infections, Mycobacterium lepraemurium, Species Specificity}, author = {Satoh M and Izaki S and Kon S and Izaki M}, title = {Fibrin and collagen deposition and fibroblasts proliferation in granuloma of murine leprosy. Comparison of two mouse strains with different immune reactions.}, abstract = {
Comparative immunofluorescence study with murine lepromas induced in C57BL/6NJcl (immunologically high responder) and CBA/N (low responder) mouse strains revealed that fibrin formation was associated with cell-mediated immune resistance against invasive bacilli. Histochemistry on paraffin sections further elucidated fibroblast proliferation and formation of collagen fibers following fibrin deposition only in murine lepromas with positive host reactions.
}, year = {1983}, journal = {Experientia}, volume = {39}, pages = {899-902}, month = {1983 Aug 15}, issn = {0014-4754}, doi = {10.1007/bf01990428}, language = {eng}, }