@article{15449, keywords = {Humans, Leprostatic Agents, leprosy, T-Lymphocytes, Tuberculosis, Cutaneous}, author = {Sarno E N and Kaplan G and Alvaranga F and Nogueira N and Porto J A and Cohn Z A}, title = {Effect of treatment on the cellular composition of cutaneous lesions in leprosy patients.}, abstract = {

We report on the cellular composition of the cutaneous lesions of 38 leprosy patients prior to and after 12-18 months of chemotherapy. All of the patients with tuberculoid (TT) disease had OKT4/OKT8 ratios that exceeded 1.0. In the indeterminate patients, the ratio varied depending upon the immune status of the individual. A low ratio of OKT4/OKT8 cells (0.25) was found in the LL patients as previously reported. The low ratio of OKT4/OKT8 in the lesions of lepromatous patients did not undergo significant changes after treatment in spite of a marked reduction in the number of intracellular bacilli.

}, year = {1984}, journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association}, volume = {52}, pages = {496-500}, month = {1984 Dec}, issn = {0148-916X}, language = {eng}, }