@article{15292, keywords = {Adolescent, Adult, Aged, Cytotoxicity, Immunologic, Erythema Nodosum, Humans, leprosy, Lymphocyte Activation, Lymphocyte Culture Test, Mixed, Middle Aged, T-Lymphocytes}, author = {Stach J L and Strobel M and Fumoux F and Bach J F}, title = {Defect in the generation of cytotoxic T cells in lepromatous leprosy.}, abstract = {
Cytotoxic T cells are consistently produced in normal individuals after in vitro stimulation by a pool of mitomycin-treated normal lymphocytes. Patients suffering from lepromatous leprosy (LL), presenting with large amounts of Mycobacterium leprae and without a history of erythema nodosum leprosum (ENL) are unable to generate such cytotoxic T cells, while lepromatous patients with ENL which, in the present study were all deprived of M. leprae, react normally.
}, year = {1982}, journal = {Clinical and experimental immunology}, volume = {48}, pages = {633-40}, month = {1982 Jun}, issn = {0009-9104}, language = {eng}, }