@article{14560,
  keywords = {Blood Proteins, Humans, Immunoglobulin A, Immunoglobulin M, Immunoglobulins, leprosy},
  author = {Gupta S C and Sinha S N and Sharma D and Bajaj A K and Bisht D and Mehrotra T N and Gupta R M},
  title = {Serum proteins and immunoglobulins in leprosy.},
  abstract = {<p>Serum proteins and immunoglobulins were studied in patients suffering from various types of leprosy. A significant increase in total protein and decrease in albumin was found in all types of leprosy except borderline-tuberculoid. Gamma globulin was found to be increased in all types. An increase of alpha-2-globulin in lepromatous, a decrease of beta globulin in borderline-lepromatous, and a decrease of alpha-2 and increase of beta globulin in borderline-tuberculoid were observed. These changes do not seem to be of diagnostic importance. A statistically significant increase of IgG in borderline-lepromatous and lepromatous, IgM in all types of leprosy and IgA only in lepromatous was found. The increase of different immunoglobulins in leprosy, especially the lepromatous type, suggests a humoral response which was found to be directly proportional to the severity of the lesion.</p>},
  year = {1978},
  journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association},
  volume = {46},
  pages = {9-13},
  month = {1978 Jan-Mar},
  issn = {0148-916X},
  language = {eng},
}