@article{1341,
  keywords = {Adolescent, Adult, Age Factors, Antibodies, Bacterial, Antigens, Bacterial, Child, Child, Preschool, Enzyme-Linked Immunosorbent Assay, Female, Glycolipids, Humans, Immunoglobulin M, India, Infant, leprosy, Longitudinal studies, Male, Middle Aged, Mycobacterium leprae, Prevalence, Sex Factors},
  author = {Krishnamurthy P and Rao P S and Reddy B N and Subramanian M and Dhandayudapani S and Bhatia V and Neelan P N and Dutta A},
  title = {Seroepidemiological study of leprosy in a highly endemic population of south India based on an ELISA using synthetic PGL-I.},
  abstract = {<p>As part of a continuing longitudinal immuno-epidemiological study, blood samples were collected by finger prick from 4243 individuals living in a highly endemic area for leprosy in South India. The samples were tested for IgM antibodies against phenolic glycolipid-I using an ELISA. Seropositivity defined as optical density greater than or equal to 0.2000 was marginally higher in the age group 10-30 years and in females. There was no evidence for a higher level in contacts than in non-contacts. The future prospect for the large scale use of this ELISA in high-endemic populations in special epidemiological investigations or routine control programs as a serological tool to detect leprosy infection appears questionable.</p>
},
  year = {1991},
  journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association},
  volume = {59},
  pages = {426-31},
  month = {1991 Sep},
  issn = {0148-916X},
  url = {http://ila.ilsl.br/pdfs/v59n3a06.pdf},
  language = {eng},
}