@article{13115,
  keywords = {Animals, Disease Models, Animal, Humans, leprosy, Liver, Mycobacterium leprae, Snakes, Spleen, Tissue Extracts},
  author = {Kwapinski J B and Kwapinski E H},
  title = {Pathobiological relationships between Mycobacterium leprae and its primitive host.},
  abstract = {<p>Newborn snakes were injected with 10(2)-10(4) live or heated Mycobacterium leprae. Death occurred in 5-6 weeks. On autopsy, the snakes injected with live microorganisms showed pathological changes and numerous acid-fast bacteria were found in some organs. Material was also transferred from an experimentally infected snake to a group of normal newborn snakes, causing their death in 3 weeks. Extracts in phosphate-buffered saline, prepared from the tissues of infected snakes, were found to react with anti-M. leprae and anti-M. lepraemurium rabbit antisera. No immunodiffusion reactions were elicited by extracts from the organs of control snakes.</p>},
  year = {1974},
  journal = {Bulletin of the World Health Organization},
  volume = {50},
  pages = {473-4},
  month = {1974},
  issn = {0042-9686},
  language = {eng},
}