@article{12618, keywords = {Adrenocorticotropic Hormone, Erythema Nodosum, Histological Techniques, Humans, leprosy, Lymph Nodes, Lymphadenitis, Mycobacterium leprae, Necrosis, Prednisolone}, author = {Karat A B and Karat S and Job C K and Sudarsanam D}, title = {Acute necrotizing lepromatous lymphadenitis: an erythema-nodosum-leprosum-like reaction in lymph nodes.}, abstract = {
Histological examination of lymph-node biopsy specimens in 12 patients with erythema nodosum leprosum showed almost complete replacement of the node by lepromatous granuloma, together with considerable polymorph infiltration. Ziehl-Neelsen staining demonstrated numerous Mycobacterium leprae present in the nodes. The majority of these patients were very ill, and responded to prednisolone or corticotrophin.It is suggested that the histological appearances may represent an intensive inflammatory response in the lymph nodes followed by avascular aseptic necrosis.
}, year = {1968}, journal = {British medical journal}, volume = {4}, pages = {223-4}, month = {1968 Oct 26}, issn = {0007-1447}, doi = {10.1136/bmj.4.5625.223}, language = {eng}, }