@article{12484, keywords = {Adult, Age Factors, Humans, Lepromin, leprosy, Myanmar, Skin Tests, Time Factors}, author = {Bechelli L M and Garbajosa P G and Gyi M M and Walter J and Tamondong C}, title = {Late lepromin reaction in untreated patients with indeterminate leprosy under 21 years old in Burma.}, abstract = {

Studies on lepromin reactivity in indeterminate (I) leprosy have usually been carried out among patients in whom the disease appeared 1 or more years before testing. This may result in misleading findings because a high proportion of patients, probably those showing moderate or strong lepromin reactions, seem to progress to the tuberculoid pole of leprosy in a relatively short time (<1 year), and in many the lesions heal spontaneously. The object of the present study was to determine the frequency and intensity of late lepromin reactions (macroscopic readings) in untreated I patients aged under 21 years who had had the disease for less than 1 year. Of 209 patients tested with lepromin containing 160 x 10(6) bacilli/ml only a small proportion ( not equal 7%) showed a negative or doubtful lepromin reaction, while 61.5% were 2+ and 3+ reactors. These findings indicate that a favourable outcome may be expected in most I cases in the trial area.

}, year = {1973}, journal = {Bulletin of the World Health Organization}, volume = {48}, pages = {113-6}, month = {1973}, issn = {0042-9686}, url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481033/pdf/bullwho00174-0118.pdf}, language = {eng}, }