@article{12017,
  keywords = {Animals, Dapsone, Drug Resistance, Microbial, Foot, Humans, Leprostatic Agents, leprosy, Mice, Mycobacterium leprae, Serotonin},
  author = {Balakrishnan S and Mester L and Venkataramaniah H N and Bhatia V N},
  title = {Mouse foot-pad studies with M. leprae--effect of desoxy fructo serotonin (DFS) and related compounds.},
  abstract = {<p>Mouse foot-pad experiments were carried out to study the effects of DFS and related compounds on the multiplication of M. leprae. Of the 25 cases clinically suspected Dapsone resistance, 8 were found resistant and 14 sensitive to Dapsone by mouse foot-pad experiments. Six were resistant to DFS and 16 were sensitive. Desoxy fructo 5-hydroxy tryptophane as well as Nutrition Antileprosy (NAL) diet were also found effective in suppressing the growth of M. leprae in mouse foot-pad. Of the two liposoluble derivatives of DFS tested (DFS LS-I and DFS LS-II), DFS LS-II was found more effective in suppressing the growth of M. leprae in foot-pads of mice.</p>},
  year = {1985},
  journal = {Indian journal of leprosy},
  volume = {57},
  pages = {323-8},
  month = {1985 Apr-Jun},
  issn = {0254-9395},
  language = {eng},
}