@article{11997, keywords = {Adolescent, Adult, Animals, Dapsone, Drug Resistance, Microbial, Foot, Humans, leprosy, Mice, Mycobacterium leprae}, author = {Vaishnavi C and Ganguly N K and Kumar B and Kaur S and Chakravarti R N}, title = {Primary dapsone resistance in leprosy.}, abstract = {

20 carefully selected untreated patients of bacilliferous leprosy were investigated for primary dapsone resistance by foot pad inoculation. Mice were fed on 0.001 g% and 0.01 g% of dapsone during the period of study. Mice in the control group were given normal rodent feed only. Animals were sacrificed from 6 month onwards at 6 week intervals upto 9 months. In two animals the growth of M. leprae was not inhibited by 0.001 g% concentration of dapsone in diet, but was completely inhibited by 0.01 g% of dapsone.

}, year = {1985}, journal = {Indian journal of leprosy}, volume = {57}, pages = {507-13}, month = {1985 Jul-Sep}, issn = {0254-9395}, language = {eng}, }