@article{11974,
  keywords = {Animals, Antigens, Bacterial, Armadillos, Enzyme-Linked Immunosorbent Assay, Formaldehyde, Glycolipids, Humans, leprosy, Liver, Mycobacterium Infections, Nontuberculous, Mycobacterium leprae, Tuberculosis, Pulmonary},
  author = {Izumi S and Sugiyama K and Fujiwara T and Hunter S W and Brennan P J},
  title = {Isolation of the Mycobacterium leprae-specific glycolipid antigen, phenolic glycolipid-I, from formalin-fixed human lepromatous liver.},
  abstract = {<p>A Mycobacterium leprae-specific phenolic glycolipid antigen was purified from Formalin-fixed liver preserved from an advanced lepromatous leprosy patient. Its chemical and immunological properties were compared with those of phenolic glycolipid-I obtained from M. leprae-infected armadillo liver. Based on the findings that the glycolipids from the two sources have the same thin-layer chromatographic properties, infrared absorption spectrum, sugar composition, and seroreactivity, we conclude that large quantities of the phenolic glycolipid-I antigen are produced in human lepromatous leprosy lesions and that Formalin-fixed lepromatous livers and spleens from the prechemotherapeutic era are suitable sources of the glycolipid.</p>},
  year = {1985},
  journal = {Journal of clinical microbiology},
  volume = {22},
  pages = {680-2},
  month = {1985 Oct},
  issn = {0095-1137},
  url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC268496/pdf/jcm00111-0232.pdf},
  language = {eng},
}