@article{11843, keywords = {Animals, Antigens, Bacterial, Armadillos, BCG Vaccine, Bacterial Vaccines, Disease Models, Animal, Erythema Nodosum, HLA Antigens, Humans, leprosy, Mice, Mycobacterium leprae, Research}, title = {Research in leprosy. A report of a committee set up by the medical research council to study future prospects.}, abstract = {
Recommendations for future research in leprosy include (i) cultivation of M. leprae in vitro; (ii) genetic control of susceptibility, including twin studies and HLA typing; (iii) precise antigenic analysis of M. leprae; (iv) mechanisms involved in the macrophage response to mycobacterial infections; (v) more use of experimental models such as normal mice infected with M. lepraemurium; (vi) reassessment of the protection afforded by BCG; (vii) assessment of protection afforded by killed (armadillo) M. leprae vaccine; (viii) pathogenesis of erythema nodosum leprosum including a study of the effect of thalidomide; and (ix) development of in vitro systems for drug sensitivity testing.
}, year = {1979}, journal = {Clinical and experimental immunology}, volume = {36}, pages = {1-7}, month = {1979 Apr}, issn = {0009-9104}, url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1537685/pdf/clinexpimmunol00205-0009.pdf}, language = {eng}, }