@article{11778,
  keywords = {Adolescent, Adult, Aged, Aged, 80 and over, Child, Dimethyl Sulfoxide, Drug Combinations, Female, Histamine, Humans, leprosy, Male, Middle Aged, Nervous System Diseases, Pain, Pain Measurement, Sensory Thresholds, Thermosensing, Touch},
  author = {Jain G L and Pasricha J S and Guha S K},
  title = {An attempt to reduce the loss of pain and touch sensations in leprosy patients.},
  abstract = {<p>An attempt was made to improve the perception of pain and touch sensations at the leprosy lesions. The loss of pain and touch sensations in a lesion was graded using Pain/Touch-Sensation-Testing-and-Grading devices. Application of a solution containing 1 mg of histamine per ml of DMSO, at the affected area decreased the grades of the loss of pain sensation in 11 (31.4%) patients and of touch sensation in 8 (22.8%) patients, out of the 35 patients tested, indicating an improvement in the perception at the lesion. This effect, however, did not persist even for 5 minutes. A higher concentration (2 mg/ml) of histamine produced reduction in the sensory loss in a larger percentage (47% for pain and 35.3% for touch) of patients, though the duration of this effect was still not prolonged.</p>},
  year = {1986},
  journal = {Indian journal of leprosy},
  volume = {58},
  pages = {225-32},
  month = {1986 Apr-Jun},
  issn = {0254-9395},
  language = {eng},
}