@article{11196,
  keywords = {Complement C3, Erythema Nodosum, Humans, Immunoglobulin A, Immunoglobulin G, Immunoglobulin M, leprosy, Leukocyte Count, T-Lymphocytes},
  author = {Sehgal V N and Gautam R K and Sharma V K},
  title = {Immunoprofile of reactions in leprosy.},
  abstract = {<p>The immunologic profile during erythema nodosum leprosum (ENL) revealed increased percentage and absolute count of B-lymphocytes, in addition to considerably lowered levels of complement component C3. Serum immunoglobulins--IgG, IgA, and IgM--were significantly raised after subsidence of ENL, whereas upgrading reaction showed an increase of absolute count of total T lymphocytes and percentage and count of B-lymphocytes. In addition, a raised serum IgM level was noted after regression of ENL. Downgrading reaction demonstrated a decreased percentage of early T-lymphocytes and raised the absolute count of B-lymphocytes. Serum IgA levels were found to be increased after amelioration of ENL.</p>},
  year = {1986},
  journal = {International journal of dermatology},
  volume = {25},
  pages = {240-4},
  month = {1986 May},
  issn = {0011-9059},
  doi = {10.1111/j.1365-4362.1986.tb02233.x},
  language = {eng},
}