@article{11190, keywords = {Humans, Interleukin-1, leprosy}, author = {Band H}, title = {Interleukin 1--a possible mediator of neural fibrosis in leprosy.}, abstract = {
Neural fibrosis in leprosy, the disease caused by the obligate intracellular bacterium, Mycobacterium leprae, is closely related to the cell-mediated immune response to this microorganism. The fibrosis appears to be due to soluble mediators released by the immune effector cells. Interleukin 1, a macrophage product that stimulates fibroblast migration, proliferation and synthetic activity, possesses the requisite properties to qualify for such a mediator.
}, year = {1986}, journal = {Medical hypotheses}, volume = {20}, pages = {143-50}, month = {1986 Jun}, issn = {0306-9877}, doi = {10.1016/0306-9877(86)90120-9}, language = {eng}, }