@article{11023, keywords = {Antigens, Bacterial, Enzyme-Linked Immunosorbent Assay, Glycolipids, Humans, Immunoglobulin M, leprosy, Longitudinal studies, Mycobacterium leprae, Papua New Guinea, Prospective Studies, Rural Population}, author = {Baumgart K and Britton W and Basten A and Bagshawe A}, title = {Use of phenolic glycolipid 1 for serodiagnosis of leprosy in a high prevalence village in Papua New Guinea.}, abstract = {

This study reports on the usefulness of an IgM phenolic glycolipid 1 (PGL-1) ELISA for serodiagnosis of leprosy in the first year of a prospective longitudinal community survey in a high (8.8%) prevalence village in Papua New Guinea. The IgM PGL-1 ELISA had limited value as a screening method for detection of new cases. Many normal persons, particularly children, had elevated IgM anti-PGL-1 antibodies, presumably a consequence of early subclinical infection.

}, year = {1987}, journal = {Transactions of the Royal Society of Tropical Medicine and Hygiene}, volume = {81}, pages = {1030-2}, month = {1987}, issn = {0035-9203}, doi = {10.1016/0035-9203(87)90388-9}, language = {eng}, }