@article{10945,
  keywords = {Acetylation, Adolescent, Adult, Dapsone, Drug Resistance, Microbial, Female, Humans, leprosy, Male, Mycobacterium leprae, Sulfamethazine},
  author = {Balakrishnan S and Ramu G},
  title = {Blood DDS levels and acetylation rates of sulphadimidine in leprosy patients.},
  abstract = {<p>The plasma DDS clearance rates and the acetylation rates of Sulphadimidine were studied in a group of 30 leprosy patients comprising of 17 non-responders and 13 responders to DDS treatment. No differences in the acetylator type or in the plasma DDS clearance were seen between the responders and non-responders. Acetylation rate did not bear any relation to the plasma clearance of DDS in the non-responders. The findings indicate that the resistance to DDS therapy in these patients is not related to any abnormal metabolic disposition of DDS.</p>},
  year = {1977},
  journal = {Leprosy in India},
  volume = {49},
  pages = {59-64},
  month = {1977 Jan},
  issn = {0024-1024},
  language = {eng},
}