@article{10628,
  keywords = {Antigens, Bacterial, Humans, Interferon-gamma, leprosy, Mycobacterium leprae, Skin Tests},
  author = {Suso L and Nogueira N and Vieira L M and Figueiredo A A and Porto J A and Sarno E N},
  title = {[Correlation of skin tests and the production of gamma-interferon in leprosy patients].},
  abstract = {<p>The responsiveness of 25 leprosy patients to an in vitro correlate of cell-mediated immunity to M. leprae antigen, (the production of Y-IFN by peripheral blood mononuclear cells) was compared to their response to skin tests routinely used to evaluate cell-mediated immunity to a number of antigens including M. leprae. The results indicate that among the polar lepromatous patients (LL) there was a clear correlation between low responses in the in vitro assay (Y-IFN production), negative skin test to the specific antigen (Mitsuda reaction) and low responses to skin tests to a related antigen (PPD). There was no correlation in the other clinical groups with skin tests to other unrelated antigens.</p>},
  year = {1988},
  journal = {Medicina cutanea ibero-latino-americana},
  volume = {16},
  pages = {193-6},
  month = {1988},
  issn = {0210-5187},
  language = {por},
}