@article{10504,
  keywords = {Autoantibodies, Humans, Leishmaniasis, leprosy, Malaria, Male, onchocerciasis elimination mapping, Parasitic Diseases, Schistosomiasis mansoni, Trypanosomiasis, Tuberculosis, Tubulin},
  author = {Howard M K and Gull K and Miles M A},
  title = {Antibodies to tubulin in patients with parasitic infections.},
  abstract = {<p>Sera from a total of 268 patients with protozoan, helminth, bacterial (leprosy and tuberculosis) infections or appropriate controls, were assayed for anti-tubulin antibodies in an indirect enzyme-linked immunosorbent assay (ELISA), using purified tubulin as antigen. Levels of serum anti-tubulin antibody were significantly elevated in 67% of patients with visceral leishmaniasis, in 60% of patients with cutaneous leishmaniasis, in 89% of patients with onchocerciasis, in 100% of patients with schistosomiasis, and in 94% of patients with leprosy. Little or no increase in anti-tubulin antibody levels was seen in sera from patients with malaria (Plasmodium vivax) or tuberculosis.</p>},
  year = {1987},
  journal = {Clinical and experimental immunology},
  volume = {68},
  pages = {78-85},
  month = {1987 Apr},
  issn = {0009-9104},
  language = {eng},
}