@article{104140,
  keywords = {coronavirus disease, Hansen’s disease, Leprosy Disease, Leprosy reactions},
  author = {Hammad RRM and Abdel-Alaeem HL and Khalaf-Allah SM},
  title = {Leprosy disease and its reactions in the era of corona virus disease 2019},
  abstract = {<p><strong>Background</strong></p>

<p>Coronavirus disease 2019 (COVID-19) is a serious worldwide health problem that affects direct and indirect however, the implications of COVID-19 co-infection in patients with Hansen’s disease remain uncertain this study aimed to assess the relationship between COVID-19 and leprosy and its reactions.</p>

<p><strong>Patients and methods</strong></p>

<p>This is a descriptive retrospective study conducted on 200 patients presented with different clinical forms of leprosy, according to COVID-19 infection, they divided into two groups, group I=98 COVID-19 positive patients and group II=102 COVID-19 negative patients.</p>

<p><strong>Results</strong></p>

<p>Significant decrease in COVID-19 co-infection among lepromatous leprosy patients with a significant decrease in leprosy reactions. Significant increase in COVID-19 co-infection among tuberculoid patients with a significant increase in leprosy reactions and in number of lepra bacilli detected by slit skin smear among COVID-19 negative patients ( P &lt;0.05). No significant difference between the two groups as regards the classification of leprosy, mode of infection of leprosy, and grade of disability ( P &gt;0.05).</p>

<p><strong>Conclusion</strong></p>

<p>COVID-19 co-infection may enhance leprosy reactions.</p>
},
  year = {2026},
  journal = {Al-Azhar Assiut Medical Journal},
  volume = {24},
  pages = {435 - 439},
  month = {09/2026},
  publisher = {Ovid Technologies (Wolters Kluwer Health)},
  issn = {1687-1693, 2536-9652},
  url = {https://www.ovid.com/jnls/aamj/pdf/10.4103/azmj.azmj_50_23~leprosy-disease-and-its-reactions-in-the-era-of-corona-virus},
  doi = {10.4103/azmj.azmj_50_23},
  language = {ENG},
}