@article{10371,
  keywords = {Corynebacterium, DNA, Bacterial, Genes, Bacterial, Humans, Kinetics, leprosy, Mycobacterium bovis, Mycobacterium leprae, Nocardia, Nucleic Acid Hybridization, Sequence Homology, Nucleic Acid},
  author = {Antoine I and Coene M and Cocito C},
  title = {Size and homology of the genomes of leprosy-derived corynebacteria, Mycobacterium leprae, and other corynebacteria and mycobacteria.},
  abstract = {<p>The genomes of Mycobacterium leprae and leprosy-derived corynebacteria (LDC), which have a similar base composition of guanine + cytosine 56 mol %, have been compared with those of reference bacteria of the CMN group (genera Corynebacterium, Mycobacterium, Nocardia). Genome sizes of three LDC strains were (1.2-2.5) x 10(6) base pairs. DNA from four of seven LDC strains examined had homology levels greater than 60%. Two other strains had a homology of 40% when compared with the CMN strains and one strain was distinctly different. The DNA from all seven LDC strains gave 0.3-18% hybridisation with that of M. leprae, 5-16% with reference corynebacteria, 5-12% with M. bovis, and 2-8% with Nocardia caviae. The small size of the LDC genome and its unrelatedness to those of M. leprae and organisms of the CMN group shows the uniqueness of LDC.</p>},
  year = {1988},
  journal = {Journal of medical microbiology},
  volume = {27},
  pages = {45-50},
  month = {1988 Sep},
  issn = {0022-2615},
  doi = {10.1099/00222615-27-1-45},
  language = {eng},
}