@article{103421, keywords = {pure neural leprosy, Case report, Child, diagnostic challenges}, author = {Santana H and Diamantino I and Arruda J and da Silva P and Santos G and de Oliveira J and de Souza V and Costa C and Macke A and Teles K and Vieira F and Lima F and Lima J}, title = {Pure neural leprosy in a child: case report and diagnostic challenges.}, abstract = {

Pure neural leprosy (PNL) is infrequent and manifests exclusively in the peripheral nerves without skin involvement, making the diagnosis more complex. We report the case of a 10-year-old child with muscle atrophy and sensory loss, diagnosed through clinical evaluation, grade 2 disability, and a positive anti-PGL-I test. The slit-skin smear (SSS) was negative for acid-fast bacilli. After 12 months of multidrug therapy, esthesiometric sensitivity improved; however, neurological deficits persisted, requiring anti-inflammatory treatment and physiotherapy. This case highlights the importance of early diagnosis and treatment for preventing disabilities. Tools, such as anti-PGL-I tests and imaging, are crucial, particularly in resource-limited settings.

}, year = {2026}, journal = {Revista da Sociedade Brasileira de Medicina Tropical}, volume = {59}, pages = {1-6}, month = {01/2026}, issn = {1678-9849}, url = {https://pmc.ncbi.nlm.nih.gov/articles/PMC12990783/pdf/1678-9849-rsbmt-59-e0158-2025.pdf}, doi = {10.1590/0037-8682-0158-2025}, language = {ENG}, }