@article{103237, keywords = {Lepromatous leprosy diagnosis, Tuberculosis, Diagnostic test, Hermatologic Manifestations}, author = {González JFM and González ALR and Gamiño AED and López LC and Moreno FAR and García AVP and Sanchez MN and Montalvo CMG and Esquivel KGS and López MA and Romo AC and Rodríguez JG and Basurto IN and Herrera SRE and Martínez MJS and Velasco KTG and Durón AXM}, title = {Concurrent Lepromatous Leprosy and Active Tuberculosis in A Young Male: A Complex Diagnostic and Therapeutic Challenge with Hematologic Manifestations}, abstract = {This report details the clinical evolution of a 23-year-old male presenting with the exceptionally rare co-occurrence of active lepromatous lerosy and tuberculous lymphadenitis, complicated by severe immune thrombocytopenia. The patient’s presentation—spanning chronic dermatological findings, acute systemic symptoms, and profound hematological disturbance—required a multifaceted diagnostic approach culminating in histopathological and microbiological confirmation of both mycobacterial infections. Management was successfully integrated, utilizing a single rifampin-based antitubercular regimen to simultaneously address both diseases, resulting in resolution of thrombocytopenia and significant clinical improvement. This case highlights the diagnostic complexity in co-endemic regions, the potential for tuberculosis to drive significant parainfectious hematologic complications, and the feasibility of a unified pharmacological strategy for dual mycobacterial disease.}, year = {2025}, journal = {International Journal of Medical Science and Clinical Research Studies}, volume = {05}, pages = {2058-2062}, month = {12/2025}, publisher = {Everant Journals}, issn = {2767-8326, 2767-8342}, url = {https://www.researchgate.net/publication/399198549_Concurrent_Lepromatous_Leprosy_and_Active_Tuberculosis_in_A_Young_Male_A_Complex_Diagnostic_and_Therapeutic_Challenge_with_Hematologic_Manifestations/fulltext/695429bc27359023a011d2ab/Concurrent-Lepromato}, doi = {10.47191/ijmscrs/v5-i12-20}, language = {ENG}, }