@article{103206,
  keywords = {HTLV-1, Coinfection, Leprosy},
  author = {Faria LGAP and Moura MN and da Cruz ALB and Andrade FDO and Cerqueira APN and Cariús LF and Novaes AF and Ribeiro SO and Takenami I and Barreto FK and Costa DT},
  title = {Type 1 leprosy reaction in a patient coinfected with HTLV-1 and Mycobacterium leprae},
  abstract = {<p>Coinfection with HTLV-1 and&nbsp;<em>Mycobacterium leprae</em>&nbsp;can present significant clinical challenges due to their complex interactions. The chronic immune activation induced by HTLV-1 can potentiate leprosy-related neurological symptoms, complicating treatment. This report describes a 61-year-old man from a Brazilian endemic area for HTLV-1 and leprosy, who was diagnosed with both infections and developed a type 1 leprosy reaction. The patient presents a significant exacerbation of neurological symptoms, with sensory and motor impairments across multiple limbs. Routine screening for HTLV-1 in patients diagnosed with leprosy, especially in endemic areas, is essential for better clinical management and prognosis.</p>
},
  year = {2026},
  journal = {Clinical Microbiology Newsletter},
  volume = {54},
  pages = {14-17},
  month = {03/2026},
  publisher = {Elsevier BV},
  issn = {0196-4399},
  url = {https://pdf.sciencedirectassets.com/271317/1-s2.0-S0196439925X00076/1-s2.0-S0196439925000704/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEKj%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJHMEUCIB5huC9n%2FtsS2mXGsMnw2HzCeTtIHRF3ndtjjfTx1hSnAiEAmcdQ%2FicF},
  doi = {10.1016/j.clinmicnews.2025.12.001},
  language = {ENG},
}