@article{103084,
  keywords = {Hansen disease, Mycobacterium leprae , Delayed Diagnosis, Symptoms, medical protocols, bacterial cultures},
  author = {Khallouki M and Bendaoud L and Serghini S and Houbayeli M and Aboudourib M and Hocar O and Amal S},
  title = {Rare multisystemic complications with delayed diagnosis in two cases of leprosy},
  abstract = {<p>Leprosy is a multisystem granulomatous disease caused by infection with Mycobacterium leprae. Herein, we report two cases of delayed diagnosis of leprosy with multisystemic involvement. A 48-year-old male patient presented with leonine facies, generalized infiltrated plaques, paresthesias, amyotrophy of the dorsal muscles of the hands, and hypoesthesia of the lower limbs evolving for three years. A 63-year-old male patient presented with infiltrated plaques of the face, hypoesthesia of the feet, acro-osteolysis of the fingers and toes, and paresthesias, all of an undetermined chronic course. The two patients were diagnosed with multibacillary leprosy on the basis of the positive bacteriological sampling of the ear lobe. The patients had multisystem involvement: neurological, bone, ocular, and nasal. The patients received the recommended treatment regimen based on dapsone, clofazimine, and rifampicin. Physicians should be vigilant in screening and treating new active cases of leprosy even in the post-leprosy elimination era.</p>
},
  year = {2025},
  journal = {Our Dermatology Online},
  volume = {16},
  publisher = {Our Dermatology Online},
  issn = {2956-7904},
  doi = {10.7241/ourd.20254.12},
  language = {ENG},
}