@article{102831,
  keywords = {Leprosy, FNAC, Lymph Nodes, Slit skin smear},
  author = {Chitkara F and Pannu D and Saha D and Makhija A and Kour I and Dhawan V and Kediya A},
  title = {Lepromatous Lymphadenitis: A Rare Manifestation of LeprosyDiagnosed by Fine Needle Aspiration Cytology},
  abstract = {<p><strong>Introduction</strong></p>

<p>Leprosy is a widespread infectious and contagious disease with a preva-lence rate of 0.4 per 10,000 population in India. It is a chronic infectious disease causedby Mycobacterium leprae and mainly affects the skin, the peripheral nerves, the mucosaof the upper respiratory tract, and the eyes. Lymph node involvement is rare.</p>

<p><strong>Case Description</strong></p>

<p>A 24-year-old male presented with right lower limb numbnessfor one year and a non-healing knee ulcer for one month, along with recurrent ulcers,sensory loss, and erythematous macules. Nerve conduction studies showed that thebilateral ulnar and sural nerves were non-excitable, and the median nerves had reducedamplitude. FNAC of a right inguinal lymph node revealed foamy macrophages andill-defined granulomas; Modified Ziehl-Neelsen stain demonstrated numerous acid-fastbacilli, indicating lepromatous lymphadenitis. A punch biopsy from the knee ulcershowed epithelioid granulomas, foamy macrophages, and a Grenz zone with positiveAFB staining. A diagnosis of Borderline Lepromatous (BL) leprosy was confirmed.The patient was started on multidrug therapy and showed clinical improvement.</p>

<p><strong>Conclusion</strong></p>

<p>When Leprosy presents as lymphadenopathy, FNAC can be a very usefultool for the diagnosis of Lymphadenopathy due to Leprosy and excludes other possi-bilities of Lymphadenitis. It is also a simpler, quicker, and less invasive technique fordiagnosing such rare lesions<br />
&nbsp;</p>
},
  year = {2025},
  journal = {Annals of Pathology and Laboratory Medicine},
  pages = {1-5},
  url = {https://pacificejournals.com/journal/index.php/apalm/article/view/3483/2292},
  language = {ENG},
}