@article{102778,
  keywords = {Leprosy, Type 1 reaction, Type 2 reaction, Multi Drug  Therapy},
  author = {Qi X and Huang S},
  title = {Unusual sequential type I and II reactions in lepromatous leprosy: a case report},
  abstract = {<p>Leprosy is a rare and easily misdiagnosed infectious disease in China. Leprosy reactions (LRs) are the greatest challenge in the treatment of leprosy. If LRs cannot be identified early and treated in a timely manner, patients are at risk of developing disabilities. Type I reactions often occur in borderline leprosy, whereas type II reactions are more prevalent in lepromatous leprosy. Clinically, lepromatous leprosy with type I and II mixed LRs is less common. This report details a case of lepromatous leprosy with mixed LRs, where the patient sequentially developed type II and then type I reactions. Through 1&nbsp;y of multidrug therapy and our timely identification and intervention for LRs during treatment, the patient achieved a successful cure without any sequelae.</p>
},
  year = {2025},
  journal = {Transactions of The Royal Society of Tropical Medicine and Hygiene},
  publisher = {Oxford University Press (OUP)},
  issn = {0035-9203, 1878-3503},
  doi = {10.1093/trstmh/traf097},
  language = {ENG},
}