@article{102571, keywords = {Adverse effects, Steroids, leprosy, Mycobacterium leprae, leprosy incognito}, author = {Nanda S and Sushantika S and Saini K and Kumar A}, title = {“Leprosy incognito”: A case report of unusual presentation of topical steroid-modified leprosy}, abstract = {

Summary Leprosy, one of the great imitators, can present with diverse clinical manifestations, often making it challenging to diagnose. We report an unusual case of steroid-modified leprosy in a 50-year-old man who presented with an erythematous, atrophic plaque with telangiectasia over the left periorbital area and mild sensory loss. The lesion had intensified in redness after prolonged application of topical corticosteroids prescribed for presumed contact dermatitis. Histopathology revealed granulomatous inflammation with perineural involvement. Slit-skin smear confirmed Mycobacterium leprae (BI-2+, MI-10%). A diagnosis of TT Hansen’s was made, and WHO-recommended multidrug therapy was initiated. The absence of acute inflammation ruled out a type 1 lepra reaction. The clinical appearance mimicked topical steroiddamaged facies, highlighting the need to consider leprosy as a differential of atypical steroid-modified dermatoses. To our knowledge, this is the first report of “leprosy incognito,” an entity analogous to tinea incognito, underscoring the importance of awareness to avoid diagnostic delays.

}, year = {2025}, journal = {Leprosy Review}, volume = {96}, publisher = {Lepra}, issn = {2162-8807}, url = {https://www.researchgate.net/profile/Dr-Sushantika/publication/394324346_Leprosy_incognito_A_case_report_of_unusual_presentation_of_topical_steroid-modified_leprosy/links/6892ec4542b47114347c7150/Leprosy-incognito-A-case-report-of-unusual-presentation-of-}, doi = {10.47276/lr.96.3.2025056}, language = {eng}, }