01011nas a2200169   4500000000100000008004100001653001800042653001500060653003900075100001700114245009300131856007700224300001000301490000600311520051000317022001400827       2014                            d10aCollaboration10aDrug Costs10aNeglected tropical diseases (NTDs)1 aPollastri MP00aFinding new collaboration models for enabling neglected tropical disease drug discovery.  uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081034/pdf/pntd.0002866.pdf  ae28660 v83 aSome of the best practices in industrial drug discovery, which include careful compound design, streamlined synthesis, compound assessment via a well-defined testing cascade, plus informatics implementation to interpret the experimental results, are now being applied to NTD drug discovery. This environment has produced credible, early-stage drug discovery programs that are more likely to produce new therapies for NTDs in the coming years and fill the pipelines within product development partnerships.  a1935-2735